Leukemia is a clonal hyperplasia of malignant cells: clinical classification 01234567

A recent patient has asked about the classification of leukemia. Today I will simply talk about the type of the disease and hope to help everyone.

Learn about the pathogenesis of leukemia:

Leukemia is a group of highly heterogeneous The malignant hematological disease, commonly known as blood cancer, originates from a genetic mutation in hematopoietic stem cells and is clonal hyperplasia. Leukemia cells in their clones lose their ability to further differentiate and mature and arrest at different stages of cell development.

A large number of abnormal growth of leukemia cells in bone marrow and other hematopoietic tissues leads to the suppression of growth of three normal blood cells and infiltration of various organs and tissues in the body, which causes a series of symptoms. The symptoms of this disease often have anemia, hemorrhage, infection and various degrees of liver, spleen, lymphadenopathy, sternal tenderness and other symptoms and signs, and the peripheral blood leukocytes have qualitative and quantitative changes.

Simply talk about the classification of leukemia:

Classify leukemia according to the maturity and natural course of leukemia cells Acute leukemia and chronic leukemia, and then according to their different white blood cell series to make a corresponding classification.

Acute leukemia: Multiple illnesses, serious illness, natural course usually within 6 months (not systemic treatment). The bone marrow and peripheral blood are mainly abnormal primary cells and early naive cells.

Chronic leukemia: slow onset, slow development, usually more than one year (not systemic treatment), bone marrow Most mature cells with peripheral blood account for the majority.

The cell differentiation of acute leukemia is arrested at an early stage, and multiple primordial cells and early naive cells are classified according to cell morphology:Acute Lymphocytic leukemia ALL and acute non-lymphocytic leukemia ANLL.

ALL is divided into L1, L2, and L3 types, and ANLL is divided into 8 types: M0 acute myeloid leukemia differentially differentiated, M1 acute myeloid leukemia undifferentiated, M2 acute myeloid leukemia partial differentiation, M3 acute promyelocytic leukemia, M4 acute mononuclear leukemia, M5 acute monocytic leukemia, M6 acute erythroleukemia, M7 acute megakaryoblastic leukemia.

The cell differentiation of chronic leukemia is arrested at a later stage, mostly mature immature cells and mature cells, which can be divided into chronic myeloid leukemia, chronic lymphoid Cellular leukemia and rare hairy cell leukemia, juvenile lymphocytic leukemia, etc., whether it is acute or chronic leukemia in the treatment of the need to choose individualized programs, and strive to obtain a good prognosis as soon as possible.

『Note』

If you have questions about this article and don’t understand the disease and treatment, you can add the following WeChat The public number consults with the doctor.

Leukemia Society WeChat public number: dxbby120

There is a disease question directly in the WeChat window to send a message or article Write a message, we will do a free help answer answer (content is not visible to the outside ~)

                

                
                                    

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